c-Abl forces YAP to switch sides

Cancer research has been significantly accelerated by viewing cancer as a functional collision between 2 dichotomous sets of genes: oncogenes and tumor suppressors. Signaling pathways turn oncogenes and tumor suppressors on and off to dictate cell fate decisions. We contend that signaling also dicta...

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Detalles Bibliográficos
Autores principales: Keshet, Rom, Reuven, Nina, Shaul, Yosef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Author's Views
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905508/
https://www.ncbi.nlm.nih.gov/pubmed/27308475
http://dx.doi.org/10.4161/23723556.2014.995006
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author Keshet, Rom
Reuven, Nina
Shaul, Yosef
author_facet Keshet, Rom
Reuven, Nina
Shaul, Yosef
author_sort Keshet, Rom
collection PubMed
description Cancer research has been significantly accelerated by viewing cancer as a functional collision between 2 dichotomous sets of genes: oncogenes and tumor suppressors. Signaling pathways turn oncogenes and tumor suppressors on and off to dictate cell fate decisions. We contend that signaling also dictates opposing behaviors of a given effector.
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spelling pubmed-49055082016-06-15 c-Abl forces YAP to switch sides Keshet, Rom Reuven, Nina Shaul, Yosef Mol Cell Oncol Author's Views Cancer research has been significantly accelerated by viewing cancer as a functional collision between 2 dichotomous sets of genes: oncogenes and tumor suppressors. Signaling pathways turn oncogenes and tumor suppressors on and off to dictate cell fate decisions. We contend that signaling also dictates opposing behaviors of a given effector. Taylor & Francis 2015-01-23 /pmc/articles/PMC4905508/ /pubmed/27308475 http://dx.doi.org/10.4161/23723556.2014.995006 Text en © 2015 The Author(s). Published with license by Taylor & Francis Group, LLC http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
spellingShingle Author's Views
Keshet, Rom
Reuven, Nina
Shaul, Yosef
c-Abl forces YAP to switch sides
title c-Abl forces YAP to switch sides
title_full c-Abl forces YAP to switch sides
title_fullStr c-Abl forces YAP to switch sides
title_full_unstemmed c-Abl forces YAP to switch sides
title_short c-Abl forces YAP to switch sides
title_sort c-abl forces yap to switch sides
topic Author's Views
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905508/
https://www.ncbi.nlm.nih.gov/pubmed/27308475
http://dx.doi.org/10.4161/23723556.2014.995006
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AT shaulyosef cablforcesyaptoswitchsides

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