Histone Methyltransferase Enhancer of Zeste Homolog 2-Mediated ABCA1 Promoter DNA Methylation Contributes to the Progression of Atherosclerosis

ATP-binding cassette transporter A1 (ABCA1) plays a critical role in maintaining cellular cholesterol homeostasis. The purpose of this study is to identify the molecular mechanism(s) underlying ABCA1 epigenetic modification and determine its potential impact on ABCA1 expression in macrophage-derived...

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Detalles Bibliográficos
Autores principales: Lv, Yun-Cheng, Tang, Yan-Yan, Zhang, Ping, Wan, Wei, Yao, Feng, He, Ping-Ping, Xie, Wei, Mo, Zhong-Cheng, Shi, Jin-Feng, Wu, Jian-Feng, Peng, Juan, Liu, Dan, Cayabyab, Francisco S., Zheng, Xi-Long, Tang, Xiang-Yang, Ouyang, Xin-Ping, Tang, Chao-Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905646/
https://www.ncbi.nlm.nih.gov/pubmed/27295295
http://dx.doi.org/10.1371/journal.pone.0157265

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