Aerobic Exercise Reduces Asthma Phenotype by Modulation of the Leukotriene Pathway

INTRODUCTION: Leukotrienes (LTs) play a central role in asthma. Low- to moderate-intensity aerobic exercise (AE) reduces asthmatic inflammation in clinical studies and in experimental models. This study investigated whether AE attenuates LT pathway activation in an ovalbumin (OVA) model of asthma. M...

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Detalles Bibliográficos
Autores principales: Alberca-Custódio, Ricardo Wesley, Greiffo, Flávia Regina, MacKenzie, BreAnne, Oliveira-Junior, Manoel Carneiro, Andrade-Sousa, Adilson Santos, Graudenz, Gustavo Silveira, Santos, Angela Batista Gomes, Damaceno-Rodrigues, Nilsa Regina, Castro-Faria-Neto, Hugo Caire, Arantes-Costa, Fernanda Magalhaes, Martins, Milton De Arruda, Abbasi, Asghar, Lin, Chin Jia, Idzko, Marco, Ligeiro Oliveira, Ana Paula, Northoff, Hinnak, Vieira, Rodolfo Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905963/
https://www.ncbi.nlm.nih.gov/pubmed/27379098
http://dx.doi.org/10.3389/fimmu.2016.00237

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