Combined Expression of IFN-γ, IL-17, and IL-4 mRNA by Recall PBMCs Moderately Discriminates Active Tuberculosis from Latent Mycobacterium tuberculosis Infection in Patients with Miscellaneous Inflammatory Underlying Conditions

New biomarkers are needed for discriminating active tuberculosis (TB) from latent TB infection (LTBI), especially in vulnerable groups representing the major diagnostic challenge. This pilot study was carried out to explore the diagnostic potential of selected genes, IFN-γ, IL-17, IL-4, and FoxP3, a...

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Detalles Bibliográficos
Autores principales: Savolainen, Laura E., Kantele, Anu, Knuuttila, Aija, Pusa, Liana, Karttunen, Riitta, Valleala, Heikki, Tuuminen, Tamara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905973/
https://www.ncbi.nlm.nih.gov/pubmed/27379100
http://dx.doi.org/10.3389/fimmu.2016.00239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905973/
https://www.ncbi.nlm.nih.gov/pubmed/27379100
http://dx.doi.org/10.3389/fimmu.2016.00239

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