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Combined Expression of IFN-γ, IL-17, and IL-4 mRNA by Recall PBMCs Moderately Discriminates Active Tuberculosis from Latent Mycobacterium tuberculosis Infection in Patients with Miscellaneous Inflammatory Underlying Conditions
New biomarkers are needed for discriminating active tuberculosis (TB) from latent TB infection (LTBI), especially in vulnerable groups representing the major diagnostic challenge. This pilot study was carried out to explore the diagnostic potential of selected genes, IFN-γ, IL-17, IL-4, and FoxP3, a...
Autores principales: | Savolainen, Laura E., Kantele, Anu, Knuuttila, Aija, Pusa, Liana, Karttunen, Riitta, Valleala, Heikki, Tuuminen, Tamara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905973/ https://www.ncbi.nlm.nih.gov/pubmed/27379100 http://dx.doi.org/10.3389/fimmu.2016.00239 |
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