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Do Copy Number Changes in CACNA2D2, CACNA2D3, and CACNA1D Constitute a Predisposing Risk Factor for Alzheimer’s Disease?

Dysregulation of calcium (Ca(2+)) homeostasis is now being recognized to be a key step in the pathogenesis of Alzheimer’s disease (AD). Data from the literature, in particular the association between AD and polymorphism that interfere with Ca(2+) homeostasis indicates the presence of genetic factors...

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Detalles Bibliográficos
Autores principales: Villela, Darine, Suemoto, Claudia K., Pasqualucci, Carlos A., Grinberg, Lea T., Rosenberg, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905985/
https://www.ncbi.nlm.nih.gov/pubmed/27379157
http://dx.doi.org/10.3389/fgene.2016.00107

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