Cargando…

Pharmacometabolomic Assessment of Metformin in Non-diabetic, African Americans

Millions of individuals are diagnosed with type 2 diabetes mellitus (T2D), which increases the risk for a plethora of adverse outcomes including cardiovascular events and kidney disease. Metformin is the most widely prescribed medication for the treatment of T2D; however, its mechanism is not fully...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rotroff, Daniel M., Oki, Noffisat O., Liang, Xiaomin, Yee, Sook Wah, Stocker, Sophie L., Corum, Daniel G., Meisner, Michele, Fiehn, Oliver, Motsinger-Reif, Alison A., Giacomini, Kathleen M., Kaddurah-Daouk, Rima
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906013/ https://www.ncbi.nlm.nih.gov/pubmed/27378919 http://dx.doi.org/10.3389/fphar.2016.00135

Ejemplares similares

Pharmacometabolomic Assessments of Atenolol and Hydrochlorothiazide Treatment Reveal Novel Drug Response Phenotypes
por: Rotroff, DM, et al.
Publicado: (2015)

Current Concepts in Pharmacometabolomics, Biomarker Discovery, and Precision Medicine
por: Beger, Richard D., et al.
Publicado: (2020)

Pharmacometabolomics Informs About Pharmacokinetic Profile of Methylphenidate
por: Kaddurah‐Daouk, Rima, et al.
Publicado: (2018)

Metabolomic signatures of drug response phenotypes for ketamine and esketamine in subjects with refractory major depressive disorder: new mechanistic insights for rapid acting antidepressants
por: Rotroff, D M, et al.
Publicado: (2016)

Pharmacometabolomics Reveals Racial Differences in Response to Atenolol Treatment
por: Wikoff, William R., et al.
Publicado: (2013)

Pharmacometabolomic Signature of Ataxia SCA1 Mouse Model and Lithium Effects
por: Perroud, Bertrand, et al.
Publicado: (2013)

Purine Pathway Implicated in Mechanism of Resistance to Aspirin Therapy: Pharmacometabolomics-Informed-Pharmacogenomics
por: Yerges-Armstrong, Laura M., et al.
Publicado: (2013)

Pharmacometabolomic mapping of early biochemical changes induced by sertraline and placebo
por: Kaddurah-Daouk, R, et al.
Publicado: (2013)

Multifactor Dimensionality Reduction as a Filter-Based Approach for Genome Wide Association Studies
por: Oki, Noffisat O., et al.
Publicado: (2011)

Pharmacometabolomics of Response to Sertraline and to Placebo in Major Depressive Disorder – Possible Role for Methoxyindole Pathway
por: Zhu, Hongjie, et al.
Publicado: (2013)

Oxylipid Profile of Low‐Dose Aspirin Exposure: A Pharmacometabolomics Study
por: Ellero‐Simatos, Sandrine, et al.
Publicado: (2015)

Pharmacometabolomics Reveals That Serotonin Is Implicated in Aspirin Response Variability
por: Ellero-Simatos, S, et al.
Publicado: (2014)

Embracing Integrative Multiomics Approaches
por: Rotroff, Daniel M., et al.
Publicado: (2016)

Sphingolipid Metabolic Pathway Impacts Thiazide Diuretics Blood Pressure Response: Insights From Genomics, Metabolomics, and Lipidomics
por: Shahin, Mohamed H., et al.
Publicado: (2017)

Comparing metabolomic and pathologic biomarkers alone and in combination for discriminating Alzheimer’s disease from normal cognitive aging
por: Motsinger-Reif, Alison A, et al.
Publicado: (2013)

Metabolic Profiling of Patients with Schizophrenia
por: Kaddurah-Daouk, Rima
Publicado: (2006)

Polymorphisms in IL-1β, vitamin D receptor Fok1, and Toll-like receptor 2 are associated with extrapulmonary tuberculosis
por: Motsinger-Reif, Alison A, et al.
Publicado: (2010)

Novel human genetic variants associated with extrapulmonary tuberculosis: a pilot genome wide association study
por: Oki, Noffisat O, et al.
Publicado: (2011)

Gene set analysis methods: a systematic comparison
por: Mathur, Ravi, et al.
Publicado: (2018)

TSPAN5, ERICH3 and selective serotonin reuptake inhibitors in major depressive disorder: pharmacometabolomics-informed pharmacogenomics
por: Gupta, M, et al.
Publicado: (2016)

The steroid metabolome in women with premenstrual dysphoric disorder during GnRH agonist-induced ovarian suppression: effects of estradiol and progesterone addback
por: Nguyen, T V, et al.
Publicado: (2017)

Cheminformatics approach to exploring and modeling trait-associated metabolite profiles
por: Ash, Jeremy R., et al.
Publicado: (2019)

Pharmacometabolomic Approach to Predict QT Prolongation in Guinea Pigs
por: Park, Jeonghyeon, et al.
Publicado: (2013)

A Pharmacometabolomic Approach to Predict Response to Metformin in Early-Phase Type 2 Diabetes Mellitus Patients
por: Park, Jeong-Eun, et al.
Publicado: (2018)

Pharmacometabolomic Approach to Investigate the Response to Metformin in Patients with Type 2 Diabetes: A Cross-Sectional Study
por: Naja, Khaled, et al.
Publicado: (2023)

Pharmacometabolomics-aided Pharmacogenomics in Autoimmune Disease
por: Katsila, Theodora, et al.
Publicado: (2016)

Pharmacometabolomics in Early‐Phase Clinical Development
por: Burt, T, et al.
Publicado: (2016)

Pharmacokinetics in Pharmacometabolomics: Towards Personalized Medication
por: Jian, Jingai, et al.
Publicado: (2023)

Pharmacometabolomics Informs Viromics toward Precision Medicine
por: Balasopoulou, Angeliki, et al.
Publicado: (2016)

Pharmacometabolomics of Meglumine Antimoniate in Patients With Cutaneous Leishmaniasis
por: Vargas, Deninson Alejandro, et al.
Publicado: (2019)

Pharmacometabolomics by NMR in Oncology: A Systematic Review
por: Gómez-Cebrián, Nuria, et al.
Publicado: (2021)

Pharmacometabolomics Applied to Personalized Medicine in Urological Cancers
por: Amaro, Filipa, et al.
Publicado: (2022)

Bile acids targeted metabolomics and medication classification data in the ADNI1 and ADNIGO/2 cohorts
por: St. John-Williams, Lisa, et al.
Publicado: (2019)

Gut Microbiome-Linked Metabolites in the Pathobiology of Major Depression With or Without Anxiety—A Role for Bile Acids
por: MahmoudianDehkordi, Siamak, et al.
Publicado: (2022)

Pharmacometabolomics for the Study of Lipid-Lowering Therapies: Opportunities and Challenges
por: Gianazza, Erica, et al.
Publicado: (2023)

Pharmacometabolomics of trabectedin in metastatic soft tissue sarcoma patients
por: Corona, Giuseppe, et al.
Publicado: (2023)

Sets of coregulated serum lipids are associated with Alzheimer's disease pathophysiology
por: Barupal, Dinesh Kumar, et al.
Publicado: (2019)

Alterations in metabolic pathways and networks in Alzheimer's disease
por: Kaddurah-Daouk, R, et al.
Publicado: (2013)

Integration of pharmacometabolomics with pharmacokinetics and pharmacodynamics: towards personalized drug therapy
por: Kantae, Vasudev, et al.
Publicado: (2016)

The Personalization of Clopidogrel Antiplatelet Therapy: The Role of Integrative Pharmacogenetics and Pharmacometabolomics
por: Amin, Arwa M., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_3ie5ssuvs788ugoavj2eu00onf