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Insights into the Pathology of the α(3) Na(+)/K(+)-ATPase Ion Pump in Neurological Disorders; Lessons from Animal Models

The transmembrane Na(+)-/K(+) ATPase is located at the plasma membrane of all mammalian cells. The Na(+)-/K(+) ATPase utilizes energy from ATP hydrolysis to extrude three Na(+) cations and import two K(+) cations into the cell. The minimum constellation for an active Na(+)-/K(+) ATPase is one alpha...

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Detalles Bibliográficos
Autores principales: Holm, Thomas H., Lykke-Hartmann, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906016/
https://www.ncbi.nlm.nih.gov/pubmed/27378932
http://dx.doi.org/10.3389/fphys.2016.00209