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Multitarget Multiscale Simulation for Pharmacological Treatment of Dystonia in Motor Cortex
A large number of physiomic pathologies can produce hyperexcitability in cortex. Depending on severity, cortical hyperexcitability may manifest clinically as a hyperkinetic movement disorder or as epilpesy. We focus here on dystonia, a movement disorder that produces involuntary muscle contractions...
Autores principales: | Neymotin, Samuel A., Dura-Bernal, Salvador, Lakatos, Peter, Sanger, Terence D., Lytton, William W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906029/ https://www.ncbi.nlm.nih.gov/pubmed/27378922 http://dx.doi.org/10.3389/fphar.2016.00157 |
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