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Simvastatin and oxidative stress in humans: A randomized, double-blinded, placebo-controlled clinical trial
Simvastatin reduces the blood concentration of cholesterol by inhibiting hydroxymethylglutaryl-coenzyme A reductase, the rate-limiting enzyme in cholesterol synthesis, and thereby reduces the risk of cardiovascular disease. In addition, simvastatin treatment leads to a reduction in fluxes in mitocho...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906137/ https://www.ncbi.nlm.nih.gov/pubmed/27281490 http://dx.doi.org/10.1016/j.redox.2016.05.007 |