Understanding the Supersensitive Anti-Drug Antibody Assay: Unexpected High Anti-Drug Antibody Incidence and Its Clinical Relevance

Numbers of biotherapeutic products in development have increased over past decade. Despite providing significant benefits to patients with unmet needs, almost all protein-based biotherapeutics could induce unwanted immunogenicity, which result in a loss of efficacy and/or increase the risk of advers...

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Detalles Bibliográficos
Autores principales: Song, Sam, Yang, Lili, Trepicchio, William L., Wyant, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906211/
https://www.ncbi.nlm.nih.gov/pubmed/27340678
http://dx.doi.org/10.1155/2016/3072586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906211/
https://www.ncbi.nlm.nih.gov/pubmed/27340678
http://dx.doi.org/10.1155/2016/3072586

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