Cargando…

Rising levels of atmospheric oxygen and evolution of Nrf2

In mammals, the master transcription regulator of antioxidant defences is provided by the Nrf2 protein. Phylogenetic analyses of Nrf2 sequences are used here to derive a molecular clock that manifests persuasive evidence that Nrf2 orthologues emerged, and then diverged, at two time points that corre...

Descripción completa

Detalles Bibliográficos
Autores principales: Gacesa, Ranko, Dunlap, Walter C., Barlow, David J., Laskowski, Roman A., Long, Paul F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906274/
https://www.ncbi.nlm.nih.gov/pubmed/27297177
http://dx.doi.org/10.1038/srep27740