Cargando…

Cecropin B Represses CYP3A29 Expression through Activation of the TLR2/4-NF-κB/PXR Signaling Pathway

Cecropins are peptide antibiotics used as drugs and feed additives. Cecropin B can inhibit the expression of CYP3A29, but the underlying mechanisms remain unclear. The present study was designed to determine the mechanisms responsible for the effects of cecropin B on CYP3A29 expression, focusing on...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Xiaoqiao, Li, Xiaowen, Wang, Xiliang, Jin, Xiue, Shi, Deshi, Wang, Jun, Bi, Dingren
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906279/ https://www.ncbi.nlm.nih.gov/pubmed/27296244 http://dx.doi.org/10.1038/srep27876

Ejemplares similares

Enterococcus faecium HDRsEf1 Protects the Intestinal Epithelium and Attenuates ETEC-Induced IL-8 Secretion in Enterocytes
por: Tian, Zhongyuan, et al.
Publicado: (2016)

Chinese herbal component, Praeruptorin E, enhances anti-asthma efficacy and prevents toxicity of aminophylline by targeting the NF-κB/PXR/CYP3A4 pathway
por: Xu, Ronghua, et al.
Publicado: (2022)

Third-Generation Sequencing and Analysis of Four Complete Pig Liver Esterase Gene Sequences in Clones Identified by Screening BAC Library
por: Zhou, Qiongqiong, et al.
Publicado: (2016)

TLR7 agonist induced repression of hepatocellular carcinoma via the TLR7-IKK-NF-κB-IL6 signaling pathway
por: REN, XINGBIN, et al.
Publicado: (2016)

Activation of PXR by alantolactone ameliorates DSS-induced experimental colitis via suppressing NF-κB signaling pathway
por: Ren, Yijing, et al.
Publicado: (2019)

Alpha-ketoglutarate suppresses the NF-κB-mediated inflammatory pathway and enhances the PXR-regulated detoxification pathway
por: He, Liuqin, et al.
Publicado: (2017)

Genetic polymorphisms in PXR and NF-κB1 influence susceptibility to anti-tuberculosis drug-induced liver injury
por: Zhang, Jingwei, et al.
Publicado: (2019)

Rifaximin Improves Clostridium difficile Toxin A-Induced Toxicity in Caco-2 Cells by the PXR-Dependent TLR4/MyD88/NF-κB Pathway
por: Esposito, Giuseppe, et al.
Publicado: (2016)

Involvement of cecropin B in the formation of the Aedes aegypti mosquito cuticle
por: Liu, Wei-Ting, et al.
Publicado: (2017)

Pregnane X Receptor (PXR)-Mediated Gene Repression and Cross-Talk of PXR with Other Nuclear Receptors via Coactivator Interactions
por: Pavek, Petr
Publicado: (2016)

PXR Functionally Interacts with NF-κB and AP-1 to Downregulate the Inflammation-Induced Expression of Chemokine CXCL2 in Mice
por: Okamura, Maya, et al.
Publicado: (2020)

A PXR-Mediated Negative Feedback Loop Attenuates the Expression of CYP3A in Response to the PXR Agonist Pregnenalone-16α-Carbonitrile
por: Bailey, Ian, et al.
Publicado: (2011)

A novel cecropin B-derived peptide with antibacterial and potential anti-inflammatory properties
por: Wang, Jiarong, et al.
Publicado: (2018)

The Repression of the HMGB1-TLR4-NF-κB Signaling Pathway by Safflower Yellow May Improve Spinal Cord Injury
por: Wang, Lu, et al.
Publicado: (2021)

Genetic Variants of Pregnane X Receptor (PXR) and CYP2B6 Affect the Induction of Bupropion Hydroxylation by Sodium Ferulate
por: Gao, Lichen, et al.
Publicado: (2013)

PXR-Mediated Upregulation of CYP3A Expression by Herb Compound Praeruptorin C from Peucedanum praeruptorum Dunn
por: Huang, Ling, et al.
Publicado: (2013)

Antiretroviral Drug Metabolism in Humanized PXR-CAR-CYP3A-NOG Mice
por: McMillan, JoEllyn M., et al.
Publicado: (2018)

Antitumor effects of cecropin B-LHRH’ on drug-resistant ovarian and endometrial cancer cells
por: Li, Xiaoyong, et al.
Publicado: (2016)

Erratum to “PXR-Mediated Upregulation of CYP3A Expression by Herb Compound Praeruptorin C from Peucedanum praeruptorum Dunn”
por: Huang, Ling, et al.
Publicado: (2014)

A Cocktail of Three Virulent Phages Controls Multidrug-Resistant Salmonella Enteritidis Infection in Poultry
por: Li, Yue, et al.
Publicado: (2022)

NF-κB, JNK, and TLR Signaling Pathways in Hepatocarcinogenesis
por: Maeda, Shin
Publicado: (2010)

Optical Isomers of Atorvastatin, Rosuvastatin and Fluvastatin Enantiospecifically Activate Pregnane X Receptor PXR and Induce CYP2A6, CYP2B6 and CYP3A4 in Human Hepatocytes
por: Korhonova, Martina, et al.
Publicado: (2015)

TGEV infection up-regulates FcRn expression via activation of NF-κB signaling
por: Guo, Jinyue, et al.
Publicado: (2016)

Antibacterial Peptide CecropinB2 Production via Various Host and Construct Systems
por: Lai, Wei-Shiang, et al.
Publicado: (2016)

Importance of extra- and intracellular domains of TLR1 and TLR2 in NFκB signaling
por: Sandor, Frantisek, et al.
Publicado: (2003)

Transcriptional Regulation of CYP3A4/2B6/2C9 Mediated via Nuclear Receptor PXR by Helicid and Its Metabolites
por: Chen, Qun, et al.
Publicado: (2015)

Modulation of TLR4/NFκB Pathways in Autoimmune Myocarditis
por: Interdonato, Livia, et al.
Publicado: (2023)

Mechanism of Probiotic VSL#3 Inhibiting NF-κB and TNF-α on Colitis through TLR4-NF-κB Signal Pathway
por: WANG, Hui, et al.
Publicado: (2019)

The Impact of Lactobacillus plantarum on the Gut Microbiota of Mice with DSS-Induced Colitis
por: Zhang, Fei, et al.
Publicado: (2019)

Study on Cecropin B2 Production via Construct Bearing Intein Oligopeptide Cleavage Variants
por: Fang, Yi-Ting, et al.
Publicado: (2020)

Activation of TLR4-Mediated NFκB Signaling in Hemorrhagic Brain in Rats
por: Teng, Weiyu, et al.
Publicado: (2009)

Regulation of High-Altitude Hypoxia on the Transcription of CYP450 and UGT1A1 Mediated by PXR and CAR
por: Duan, Ya-bin, et al.
Publicado: (2020)

Rosmarinic acid represses colitis-associated colon cancer: A pivotal involvement of the TLR4-mediated NF-κB-STAT3 axis
por: Jin, Bo-Ram, et al.
Publicado: (2021)

NF-κB Repression by PIAS3 Mediated RelA SUMOylation
por: Liu, Yuangang, et al.
Publicado: (2012)

Foxp3 Interacts with c-Rel to Mediate NF-κB Repression
por: Loizou, Louiza, et al.
Publicado: (2011)

Roles of TLR7 in Activation of NF-κB Signaling of Keratinocytes by Imiquimod
por: Li, Zheng Jun, et al.
Publicado: (2013)

Cyclophilin A (CypA) Interacts with NF-κB Subunit, p65/RelA, and Contributes to NF-κB Activation Signaling
por: Sun, Shan, et al.
Publicado: (2014)

mRNA expression of TLR4, TLR9 and NF-κB in a neonatal murine model of necrotizing enterocolitis
por: Yin, Yiyu, et al.
Publicado: (2016)

Cecropins from Plutella xylostella and Their Interaction with Metarhizium anisopliae
por: Ouyang, Lina, et al.
Publicado: (2015)

The TLR4/NF-κB/MAGI-2 signaling pathway mediates postoperative delirium
por: Zhang, Wei, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ukc3mgpcgmqvcrp9md1bes37pc