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Energy Landscape Topography Reveals the Underlying Link Between Binding Specificity and Activity of Enzymes
Enzyme activity (often quantified by k(cat)/K(m)) is the main function of enzyme when it is active against the specific substrate. Higher or lower activities are highly desired for the design of novel enzyme and drug resistance. However, it is difficult to measure the activities of all possible vari...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906287/ https://www.ncbi.nlm.nih.gov/pubmed/27298067 http://dx.doi.org/10.1038/srep27808 |