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Direct interaction of beta-amyloid with Na,K-ATPase as a putative regulator of the enzyme function

By maintaining the Na(+) and K(+) transmembrane gradient mammalian Na,K-ATPase acts as a key regulator of neuronal electrotonic properties. Na,K-ATPase has an important role in synaptic transmission and memory formation. Accumulation of beta-amyloid (Aβ) at the early stages of Alzheimer’s disease is...

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Detalles Bibliográficos
Autores principales:	Petrushanko, Irina Yu., Mitkevich, Vladimir A., Anashkina, Anastasia A., Adzhubei, Alexei A., Burnysheva, Ksenia M., Lakunina, Valentina A., Kamanina, Yulia V., Dergousova, Elena A., Lopina, Olga D., Ogunshola, Omolara O., Bogdanova, Anna Yu., Makarov, Alexander A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906314/ https://www.ncbi.nlm.nih.gov/pubmed/27296892 http://dx.doi.org/10.1038/srep27738

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