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Global Profiling and Inhibition of Protein Lipidation in Vector and Host Stages of the Sleeping Sickness Parasite Trypanosoma brucei

[Image: see text] The enzyme N-myristoyltransferase (NMT) catalyzes the essential fatty acylation of substrate proteins with myristic acid in eukaryotes and is a validated drug target in the parasite Trypanosoma brucei, the causative agent of African trypanosomiasis (sleeping sickness). N-Myristoyla...

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Detalles Bibliográficos
Autores principales:	Wright, Megan H., Paape, Daniel, Price, Helen P., Smith, Deborah F., Tate, Edward W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2016
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906374/ https://www.ncbi.nlm.nih.gov/pubmed/27331140 http://dx.doi.org/10.1021/acsinfecdis.6b00034

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