Contribution of Amphipathicity and Hydrophobicity to the Antimicrobial Activity and Cytotoxicity of β-Hairpin Peptides

[Image: see text] Bacteria have acquired extensive resistance mechanisms to protect themselves against antibiotic action. Today the bacterial membrane has become one of the “final frontiers” in the search for new compounds acting on novel targets to address the threat of multi-drug resistant (MDR) a...

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Detalles Bibliográficos
Autores principales: Edwards, Ingrid A., Elliott, Alysha G., Kavanagh, Angela M., Zuegg, Johannes, Blaskovich, Mark A. T., Cooper, Matthew A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906375/
https://www.ncbi.nlm.nih.gov/pubmed/27331141
http://dx.doi.org/10.1021/acsinfecdis.6b00045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906375/
https://www.ncbi.nlm.nih.gov/pubmed/27331141
http://dx.doi.org/10.1021/acsinfecdis.6b00045

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