New Glycoconjugates for the Treatment of Diseases Related to Metal Dyshomeostasis

Metal dyshomeostasis is involved in several pathologies, making metal ions promising therapeutic targets. Conjugating 8‐hydroxyquinolines with sugars gave rise to novel derivatives with improved solubility, selectivity, and multifunctionality. Biological evaluation of these compounds suggests they h...

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Detalles Bibliográficos
Autor principal: Oliveri, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Thesis Treasury
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906504/
https://www.ncbi.nlm.nih.gov/pubmed/27308206
http://dx.doi.org/10.1002/open.201500155
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author Oliveri, Valentina
author_facet Oliveri, Valentina
author_sort Oliveri, Valentina
collection PubMed
description Metal dyshomeostasis is involved in several pathologies, making metal ions promising therapeutic targets. Conjugating 8‐hydroxyquinolines with sugars gave rise to novel derivatives with improved solubility, selectivity, and multifunctionality. Biological evaluation of these compounds suggests they have potential as therapeutic agents in diseases related to metal dyshomeostasis.[Image: see text]
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spelling pubmed-49065042016-06-15 New Glycoconjugates for the Treatment of Diseases Related to Metal Dyshomeostasis Oliveri, Valentina ChemistryOpen Thesis Treasury Metal dyshomeostasis is involved in several pathologies, making metal ions promising therapeutic targets. Conjugating 8‐hydroxyquinolines with sugars gave rise to novel derivatives with improved solubility, selectivity, and multifunctionality. Biological evaluation of these compounds suggests they have potential as therapeutic agents in diseases related to metal dyshomeostasis.[Image: see text] John Wiley and Sons Inc. 2015-07-14 /pmc/articles/PMC4906504/ /pubmed/27308206 http://dx.doi.org/10.1002/open.201500155 Text en © 2015 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Thesis Treasury
Oliveri, Valentina
New Glycoconjugates for the Treatment of Diseases Related to Metal Dyshomeostasis
title New Glycoconjugates for the Treatment of Diseases Related to Metal Dyshomeostasis
title_full New Glycoconjugates for the Treatment of Diseases Related to Metal Dyshomeostasis
title_fullStr New Glycoconjugates for the Treatment of Diseases Related to Metal Dyshomeostasis
title_full_unstemmed New Glycoconjugates for the Treatment of Diseases Related to Metal Dyshomeostasis
title_short New Glycoconjugates for the Treatment of Diseases Related to Metal Dyshomeostasis
title_sort new glycoconjugates for the treatment of diseases related to metal dyshomeostasis
topic Thesis Treasury
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906504/
https://www.ncbi.nlm.nih.gov/pubmed/27308206
http://dx.doi.org/10.1002/open.201500155
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