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Gold Nanoparticles Decorated with Sialic Acid Terminated Bi‐antennary N‐Glycans for the Detection of Influenza Virus at Nanomolar Concentrations
Invited for this month's cover picture is the group of Professor Antony Fairbanks and his collaborators at the University of Canterbury and University of Otago. The cover shows the isolation of complex bi‐antennary oligosaccharides from hens’ eggs and their conjugation to gold nanoparticles. Go...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906511/ https://www.ncbi.nlm.nih.gov/pubmed/27308188 http://dx.doi.org/10.1002/open.201500182 |
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author | Poonthiyil, Vivek Nagesh, Prashanth T. Husain, Matloob Golovko, Vladimir B. Fairbanks, Antony J. |
author_facet | Poonthiyil, Vivek Nagesh, Prashanth T. Husain, Matloob Golovko, Vladimir B. Fairbanks, Antony J. |
author_sort | Poonthiyil, Vivek |
collection | PubMed |
description | Invited for this month's cover picture is the group of Professor Antony Fairbanks and his collaborators at the University of Canterbury and University of Otago. The cover shows the isolation of complex bi‐antennary oligosaccharides from hens’ eggs and their conjugation to gold nanoparticles. Gold nanoparticles carrying these sugars can then bind to specific receptors (hemagglutinin) on the surface of the influenza virus, causing particle aggregation, which changes their spectroscopic properties. Upon aggregation, they undergo a red‐shift in their surface plasmon resonance, as illustrated by the bound particles shining in the cover image. These changes in spectroscopic properties are the basis of a detection system capable of detecting viral hemagglutinin at nanomolar concentrations, as well as the virus itself. For more details, see the Full Paper on p. 708 ff.Read the full text of the article at 10.1002/open.201500109 |
format | Online Article Text |
id | pubmed-4906511 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-49065112016-06-15 Gold Nanoparticles Decorated with Sialic Acid Terminated Bi‐antennary N‐Glycans for the Detection of Influenza Virus at Nanomolar Concentrations Poonthiyil, Vivek Nagesh, Prashanth T. Husain, Matloob Golovko, Vladimir B. Fairbanks, Antony J. ChemistryOpen Cover Profiles Invited for this month's cover picture is the group of Professor Antony Fairbanks and his collaborators at the University of Canterbury and University of Otago. The cover shows the isolation of complex bi‐antennary oligosaccharides from hens’ eggs and their conjugation to gold nanoparticles. Gold nanoparticles carrying these sugars can then bind to specific receptors (hemagglutinin) on the surface of the influenza virus, causing particle aggregation, which changes their spectroscopic properties. Upon aggregation, they undergo a red‐shift in their surface plasmon resonance, as illustrated by the bound particles shining in the cover image. These changes in spectroscopic properties are the basis of a detection system capable of detecting viral hemagglutinin at nanomolar concentrations, as well as the virus itself. For more details, see the Full Paper on p. 708 ff.Read the full text of the article at 10.1002/open.201500109 John Wiley and Sons Inc. 2015-09-30 /pmc/articles/PMC4906511/ /pubmed/27308188 http://dx.doi.org/10.1002/open.201500182 Text en © 2015 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim |
spellingShingle | Cover Profiles Poonthiyil, Vivek Nagesh, Prashanth T. Husain, Matloob Golovko, Vladimir B. Fairbanks, Antony J. Gold Nanoparticles Decorated with Sialic Acid Terminated Bi‐antennary N‐Glycans for the Detection of Influenza Virus at Nanomolar Concentrations |
title | Gold Nanoparticles Decorated with Sialic Acid Terminated Bi‐antennary N‐Glycans for the Detection of Influenza Virus at Nanomolar Concentrations
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title_full | Gold Nanoparticles Decorated with Sialic Acid Terminated Bi‐antennary N‐Glycans for the Detection of Influenza Virus at Nanomolar Concentrations
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title_fullStr | Gold Nanoparticles Decorated with Sialic Acid Terminated Bi‐antennary N‐Glycans for the Detection of Influenza Virus at Nanomolar Concentrations
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title_full_unstemmed | Gold Nanoparticles Decorated with Sialic Acid Terminated Bi‐antennary N‐Glycans for the Detection of Influenza Virus at Nanomolar Concentrations
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title_short | Gold Nanoparticles Decorated with Sialic Acid Terminated Bi‐antennary N‐Glycans for the Detection of Influenza Virus at Nanomolar Concentrations
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title_sort | gold nanoparticles decorated with sialic acid terminated bi‐antennary n‐glycans for the detection of influenza virus at nanomolar concentrations |
topic | Cover Profiles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906511/ https://www.ncbi.nlm.nih.gov/pubmed/27308188 http://dx.doi.org/10.1002/open.201500182 |
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