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An ontology-driven, case-based clinical decision support model for removable partial denture design

We present the initial work toward developing a clinical decision support model for specific design of removable partial dentures (RPDs) in dentistry. We developed an ontological paradigm to represent knowledge of a patient’s oral conditions and denture component parts. During the case-based reasoni...

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Autores principales: Chen, Qingxiao, Wu, Ji, Li, Shusen, Lyu, Peijun, Wang, Yong, Li, Miao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906524/
https://www.ncbi.nlm.nih.gov/pubmed/27297679
http://dx.doi.org/10.1038/srep27855
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author Chen, Qingxiao
Wu, Ji
Li, Shusen
Lyu, Peijun
Wang, Yong
Li, Miao
author_facet Chen, Qingxiao
Wu, Ji
Li, Shusen
Lyu, Peijun
Wang, Yong
Li, Miao
author_sort Chen, Qingxiao
collection PubMed
description We present the initial work toward developing a clinical decision support model for specific design of removable partial dentures (RPDs) in dentistry. We developed an ontological paradigm to represent knowledge of a patient’s oral conditions and denture component parts. During the case-based reasoning process, a cosine similarity algorithm was applied to calculate similarity values between input patients and standard ontology cases. A group of designs from the most similar cases were output as the final results. To evaluate this model, the output designs of RPDs for 104 randomly selected patients were compared with those selected by professionals. An area under the curve of the receiver operating characteristic (AUC-ROC) was created by plotting true-positive rates against the false-positive rate at various threshold settings. The precision at position 5 of the retrieved cases was 0.67 and at the top of the curve it was 0.96, both of which are very high. The mean average of precision (MAP) was 0.61 and the normalized discounted cumulative gain (NDCG) was 0.74 both of which confirmed the efficient performance of our model. All the metrics demonstrated the efficiency of our model. This methodology merits further research development to match clinical applications for designing RPDs. This paper is organized as follows. After the introduction and description of the basis for the paper, the evaluation and results are presented in Section 2. Section 3 provides a discussion of the methodology and results. Section 4 describes the details of the ontology, similarity algorithm, and application.
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spelling pubmed-49065242016-06-15 An ontology-driven, case-based clinical decision support model for removable partial denture design Chen, Qingxiao Wu, Ji Li, Shusen Lyu, Peijun Wang, Yong Li, Miao Sci Rep Article We present the initial work toward developing a clinical decision support model for specific design of removable partial dentures (RPDs) in dentistry. We developed an ontological paradigm to represent knowledge of a patient’s oral conditions and denture component parts. During the case-based reasoning process, a cosine similarity algorithm was applied to calculate similarity values between input patients and standard ontology cases. A group of designs from the most similar cases were output as the final results. To evaluate this model, the output designs of RPDs for 104 randomly selected patients were compared with those selected by professionals. An area under the curve of the receiver operating characteristic (AUC-ROC) was created by plotting true-positive rates against the false-positive rate at various threshold settings. The precision at position 5 of the retrieved cases was 0.67 and at the top of the curve it was 0.96, both of which are very high. The mean average of precision (MAP) was 0.61 and the normalized discounted cumulative gain (NDCG) was 0.74 both of which confirmed the efficient performance of our model. All the metrics demonstrated the efficiency of our model. This methodology merits further research development to match clinical applications for designing RPDs. This paper is organized as follows. After the introduction and description of the basis for the paper, the evaluation and results are presented in Section 2. Section 3 provides a discussion of the methodology and results. Section 4 describes the details of the ontology, similarity algorithm, and application. Nature Publishing Group 2016-06-14 /pmc/articles/PMC4906524/ /pubmed/27297679 http://dx.doi.org/10.1038/srep27855 Text en Copyright © 2016, Macmillan Publishers Limited http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Chen, Qingxiao
Wu, Ji
Li, Shusen
Lyu, Peijun
Wang, Yong
Li, Miao
An ontology-driven, case-based clinical decision support model for removable partial denture design
title An ontology-driven, case-based clinical decision support model for removable partial denture design
title_full An ontology-driven, case-based clinical decision support model for removable partial denture design
title_fullStr An ontology-driven, case-based clinical decision support model for removable partial denture design
title_full_unstemmed An ontology-driven, case-based clinical decision support model for removable partial denture design
title_short An ontology-driven, case-based clinical decision support model for removable partial denture design
title_sort ontology-driven, case-based clinical decision support model for removable partial denture design
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906524/
https://www.ncbi.nlm.nih.gov/pubmed/27297679
http://dx.doi.org/10.1038/srep27855
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