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Q&A: What are exosomes, exactly?

Exosomes are extracellular vesicles first described as such 30 years ago and since implicated in cell–cell communication and the transmission of disease states, and explored as a means of drug discovery. Yet fundamental questions about their biology remain unanswered. Here I explore what exosomes ar...

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Detalles Bibliográficos
Autor principal: Edgar, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906597/
https://www.ncbi.nlm.nih.gov/pubmed/27296830
http://dx.doi.org/10.1186/s12915-016-0268-z
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author Edgar, James R.
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description Exosomes are extracellular vesicles first described as such 30 years ago and since implicated in cell–cell communication and the transmission of disease states, and explored as a means of drug discovery. Yet fundamental questions about their biology remain unanswered. Here I explore what exosomes are, highlight the difficulties in studying them and explain the current definition and some of the outstanding issues in exosome biology.
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spelling pubmed-49065972016-06-15 Q&A: What are exosomes, exactly? Edgar, James R. BMC Biol Question and Answer Exosomes are extracellular vesicles first described as such 30 years ago and since implicated in cell–cell communication and the transmission of disease states, and explored as a means of drug discovery. Yet fundamental questions about their biology remain unanswered. Here I explore what exosomes are, highlight the difficulties in studying them and explain the current definition and some of the outstanding issues in exosome biology. BioMed Central 2016-06-13 /pmc/articles/PMC4906597/ /pubmed/27296830 http://dx.doi.org/10.1186/s12915-016-0268-z Text en © Edgar. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Question and Answer
Edgar, James R.
Q&A: What are exosomes, exactly?
title Q&A: What are exosomes, exactly?
title_full Q&A: What are exosomes, exactly?
title_fullStr Q&A: What are exosomes, exactly?
title_full_unstemmed Q&A: What are exosomes, exactly?
title_short Q&A: What are exosomes, exactly?
title_sort q&a: what are exosomes, exactly?
topic Question and Answer
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906597/
https://www.ncbi.nlm.nih.gov/pubmed/27296830
http://dx.doi.org/10.1186/s12915-016-0268-z
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