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Delineating the effect of demethylating agent 5-aza-2′-deoxycytidine on human Caco-2 colonic carcinoma cells

Aberrant epigenetic changes are known to contribute to various phases of tumor development. The gene function loss caused by aberrant methylation is analogous to genetic mutations. Unlike genetic mutations, epigenetic alterations can be reversed. 5-Aza-2′-deoxycytidine (5-aza-CdR) has been approved...

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Detalles Bibliográficos
Autores principales:	LI, XIUMEI, QIN, BINGZHAO, LIU, BO
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906626/ https://www.ncbi.nlm.nih.gov/pubmed/27347114 http://dx.doi.org/10.3892/ol.2016.4551

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