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Sinonasal spindle cell carcinoma presenting with bilateral visual loss: A case report and review of the literature

Spindle cell carcinoma (SpCC) is a rare variant of squamous cell carcinoma (SCC). SpCC of sinonasal origin is relatively rare and more aggressive than normal SCC. It most commonly involves the maxillary sinus, and rarely the sphenoid sinus. The present study reports a case of sphenoid sinus SpCC pre...

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Autores principales: LIU, TSUNG-WEI, HUNG, SHIH-HAN, CHEN, PO-YUEH
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906660/
https://www.ncbi.nlm.nih.gov/pubmed/27347158
http://dx.doi.org/10.3892/ol.2016.4620
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author LIU, TSUNG-WEI
HUNG, SHIH-HAN
CHEN, PO-YUEH
author_facet LIU, TSUNG-WEI
HUNG, SHIH-HAN
CHEN, PO-YUEH
author_sort LIU, TSUNG-WEI
collection PubMed
description Spindle cell carcinoma (SpCC) is a rare variant of squamous cell carcinoma (SCC). SpCC of sinonasal origin is relatively rare and more aggressive than normal SCC. It most commonly involves the maxillary sinus, and rarely the sphenoid sinus. The present study reports a case of sphenoid sinus SpCC presenting with bilateral visual loss. Following endoscopic sinus decompression surgery, the patient was referred to the Oncology Department for a staging workup, and subsequently received concurrent chemoradiotherapy; however, the vision of the patient was not recovered, despite treatment. To the best of our knowledge, this is the first reported case of synchronous inverted papilloma of the sphenoid sinus and SpCC presenting with optic nerve compression.
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spelling pubmed-49066602016-06-24 Sinonasal spindle cell carcinoma presenting with bilateral visual loss: A case report and review of the literature LIU, TSUNG-WEI HUNG, SHIH-HAN CHEN, PO-YUEH Oncol Lett Articles Spindle cell carcinoma (SpCC) is a rare variant of squamous cell carcinoma (SCC). SpCC of sinonasal origin is relatively rare and more aggressive than normal SCC. It most commonly involves the maxillary sinus, and rarely the sphenoid sinus. The present study reports a case of sphenoid sinus SpCC presenting with bilateral visual loss. Following endoscopic sinus decompression surgery, the patient was referred to the Oncology Department for a staging workup, and subsequently received concurrent chemoradiotherapy; however, the vision of the patient was not recovered, despite treatment. To the best of our knowledge, this is the first reported case of synchronous inverted papilloma of the sphenoid sinus and SpCC presenting with optic nerve compression. D.A. Spandidos 2016-07 2016-05-25 /pmc/articles/PMC4906660/ /pubmed/27347158 http://dx.doi.org/10.3892/ol.2016.4620 Text en Copyright: © Liu et al. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Articles
LIU, TSUNG-WEI
HUNG, SHIH-HAN
CHEN, PO-YUEH
Sinonasal spindle cell carcinoma presenting with bilateral visual loss: A case report and review of the literature
title Sinonasal spindle cell carcinoma presenting with bilateral visual loss: A case report and review of the literature
title_full Sinonasal spindle cell carcinoma presenting with bilateral visual loss: A case report and review of the literature
title_fullStr Sinonasal spindle cell carcinoma presenting with bilateral visual loss: A case report and review of the literature
title_full_unstemmed Sinonasal spindle cell carcinoma presenting with bilateral visual loss: A case report and review of the literature
title_short Sinonasal spindle cell carcinoma presenting with bilateral visual loss: A case report and review of the literature
title_sort sinonasal spindle cell carcinoma presenting with bilateral visual loss: a case report and review of the literature
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906660/
https://www.ncbi.nlm.nih.gov/pubmed/27347158
http://dx.doi.org/10.3892/ol.2016.4620
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