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Candesartan cilexetil prevents diet-induced insulin resistance via peroxisome proliferator-activated receptor-γ activation in an obese rat model

Angiotensin II type 1 receptor (AT1R) blockers (ARBs) have been shown to reduce the incidence of type 2 diabetes mellitus; however, the underlying molecular mechanism is unknown. Peroxisome proliferator-activated receptor γ (PPARγ) is the central regulator of insulin and glucose metabolism, which im...

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Detalles Bibliográficos
Autores principales:	YAN, WEN-HUA, PAN, CHANG-YU, DOU, JING-TAO, MENG, JUN-HUA, WANG, BAO-AN, MU, YI-MING
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906785/ https://www.ncbi.nlm.nih.gov/pubmed/27347049 http://dx.doi.org/10.3892/etm.2016.3297

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