Development of a novel mouse model of hepatocellular carcinoma with nonalcoholic steatohepatitis using a high-fat, choline-deficient diet and intraperitoneal injection of diethylnitrosamine

BACKGROUND: The incidence of hepatocellular carcinoma with nonalcoholic steatohepatitis is increasing, and its clinicopathological features are well established. Several animal models of nonalcoholic steatohepatitis have been developed to facilitate its study; however, few fully recapitulate all its...

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Detalles Bibliográficos
Autores principales: Kishida, Norihiro, Matsuda, Sachiko, Itano, Osamu, Shinoda, Masahiro, Kitago, Minoru, Yagi, Hiroshi, Abe, Yuta, Hibi, Taizo, Masugi, Yohei, Aiura, Koichi, Sakamoto, Michiie, Kitagawa, Yuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906823/
https://www.ncbi.nlm.nih.gov/pubmed/27296438
http://dx.doi.org/10.1186/s12876-016-0477-5

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