ABCB1 polymorphism is associated with atorvastatin-induced liver injury in Japanese population

BACKGROUND: To investigate the associations between atorvastatin-induced liver injury (AILI) and polymorphisms in eight genes possibly involved in the hepatic metabolism (CYP2C9, CYP2C19, CYP3A4, CYP3A5 and UGT1A1) and membrane transport (ABCB1, ABCG2 and SLCO1B1) of atorvastatin, we genotyped 30 AI...

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Detalles Bibliográficos
Autores principales: Fukunaga, Koya, Nakagawa, Hiroshi, Ishikawa, Toshihisa, Kubo, Michiaki, Mushiroda, Taisei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906899/
https://www.ncbi.nlm.nih.gov/pubmed/27296832
http://dx.doi.org/10.1186/s12863-016-0390-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906899/
https://www.ncbi.nlm.nih.gov/pubmed/27296832
http://dx.doi.org/10.1186/s12863-016-0390-5

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