Chromoblastomycosis due to Fonsecaea monophora misdiagnosed as sporotrichosis and cutaneous tuberculosis in a pulmonary tuberculosis patient
Chromoblastomycosis is caused by dematiaceous fungi. It develops after inoculation of the organism into the skin. We report a case of chromoblastomycosis in a pulmonary tuberculosis patient without known history of trauma. The lesions were initially diagnosed as sporotrichosis and skin tuberculosis....
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907037/ https://www.ncbi.nlm.nih.gov/pubmed/27330937 http://dx.doi.org/10.1016/j.mmcr.2016.05.001 |
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author | Shi, Dongmei Zhang, Wei Lu, Guixia de Hoog, G. Sybren Liang, Guanzhao Mei, Huan Zheng, Hailin Shen, Yongnian Liu, Weida |
author_facet | Shi, Dongmei Zhang, Wei Lu, Guixia de Hoog, G. Sybren Liang, Guanzhao Mei, Huan Zheng, Hailin Shen, Yongnian Liu, Weida |
author_sort | Shi, Dongmei |
collection | PubMed |
description | Chromoblastomycosis is caused by dematiaceous fungi. It develops after inoculation of the organism into the skin. We report a case of chromoblastomycosis in a pulmonary tuberculosis patient without known history of trauma. The lesions were initially diagnosed as sporotrichosis and skin tuberculosis. Histopathology of scales and skin biopsy specimen revealed sclerotic bodies, the hallmark of chromoblastomycosis. The causative organism was identified as Fonsecaea monophora by rDNA ITS sequencing. The lesions recovered markedly after two month treatment with oral terbinafine 250 mg daily according to drug sensitive test in vitro in combination with local thermotherapy |
format | Online Article Text |
id | pubmed-4907037 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-49070372016-06-21 Chromoblastomycosis due to Fonsecaea monophora misdiagnosed as sporotrichosis and cutaneous tuberculosis in a pulmonary tuberculosis patient Shi, Dongmei Zhang, Wei Lu, Guixia de Hoog, G. Sybren Liang, Guanzhao Mei, Huan Zheng, Hailin Shen, Yongnian Liu, Weida Med Mycol Case Rep Case Report Chromoblastomycosis is caused by dematiaceous fungi. It develops after inoculation of the organism into the skin. We report a case of chromoblastomycosis in a pulmonary tuberculosis patient without known history of trauma. The lesions were initially diagnosed as sporotrichosis and skin tuberculosis. Histopathology of scales and skin biopsy specimen revealed sclerotic bodies, the hallmark of chromoblastomycosis. The causative organism was identified as Fonsecaea monophora by rDNA ITS sequencing. The lesions recovered markedly after two month treatment with oral terbinafine 250 mg daily according to drug sensitive test in vitro in combination with local thermotherapy Elsevier 2016-05-10 /pmc/articles/PMC4907037/ /pubmed/27330937 http://dx.doi.org/10.1016/j.mmcr.2016.05.001 Text en © 2016 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Shi, Dongmei Zhang, Wei Lu, Guixia de Hoog, G. Sybren Liang, Guanzhao Mei, Huan Zheng, Hailin Shen, Yongnian Liu, Weida Chromoblastomycosis due to Fonsecaea monophora misdiagnosed as sporotrichosis and cutaneous tuberculosis in a pulmonary tuberculosis patient |
title | Chromoblastomycosis due to Fonsecaea monophora misdiagnosed as sporotrichosis and cutaneous tuberculosis in a pulmonary tuberculosis patient |
title_full | Chromoblastomycosis due to Fonsecaea monophora misdiagnosed as sporotrichosis and cutaneous tuberculosis in a pulmonary tuberculosis patient |
title_fullStr | Chromoblastomycosis due to Fonsecaea monophora misdiagnosed as sporotrichosis and cutaneous tuberculosis in a pulmonary tuberculosis patient |
title_full_unstemmed | Chromoblastomycosis due to Fonsecaea monophora misdiagnosed as sporotrichosis and cutaneous tuberculosis in a pulmonary tuberculosis patient |
title_short | Chromoblastomycosis due to Fonsecaea monophora misdiagnosed as sporotrichosis and cutaneous tuberculosis in a pulmonary tuberculosis patient |
title_sort | chromoblastomycosis due to fonsecaea monophora misdiagnosed as sporotrichosis and cutaneous tuberculosis in a pulmonary tuberculosis patient |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907037/ https://www.ncbi.nlm.nih.gov/pubmed/27330937 http://dx.doi.org/10.1016/j.mmcr.2016.05.001 |
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