Chromoblastomycosis due to Fonsecaea monophora misdiagnosed as sporotrichosis and cutaneous tuberculosis in a pulmonary tuberculosis patient

Chromoblastomycosis is caused by dematiaceous fungi. It develops after inoculation of the organism into the skin. We report a case of chromoblastomycosis in a pulmonary tuberculosis patient without known history of trauma. The lesions were initially diagnosed as sporotrichosis and skin tuberculosis....

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Autores principales: Shi, Dongmei, Zhang, Wei, Lu, Guixia, de Hoog, G. Sybren, Liang, Guanzhao, Mei, Huan, Zheng, Hailin, Shen, Yongnian, Liu, Weida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907037/
https://www.ncbi.nlm.nih.gov/pubmed/27330937
http://dx.doi.org/10.1016/j.mmcr.2016.05.001
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author Shi, Dongmei
Zhang, Wei
Lu, Guixia
de Hoog, G. Sybren
Liang, Guanzhao
Mei, Huan
Zheng, Hailin
Shen, Yongnian
Liu, Weida
author_facet Shi, Dongmei
Zhang, Wei
Lu, Guixia
de Hoog, G. Sybren
Liang, Guanzhao
Mei, Huan
Zheng, Hailin
Shen, Yongnian
Liu, Weida
author_sort Shi, Dongmei
collection PubMed
description Chromoblastomycosis is caused by dematiaceous fungi. It develops after inoculation of the organism into the skin. We report a case of chromoblastomycosis in a pulmonary tuberculosis patient without known history of trauma. The lesions were initially diagnosed as sporotrichosis and skin tuberculosis. Histopathology of scales and skin biopsy specimen revealed sclerotic bodies, the hallmark of chromoblastomycosis. The causative organism was identified as Fonsecaea monophora by rDNA ITS sequencing. The lesions recovered markedly after two month treatment with oral terbinafine 250 mg daily according to drug sensitive test in vitro in combination with local thermotherapy
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spelling pubmed-49070372016-06-21 Chromoblastomycosis due to Fonsecaea monophora misdiagnosed as sporotrichosis and cutaneous tuberculosis in a pulmonary tuberculosis patient Shi, Dongmei Zhang, Wei Lu, Guixia de Hoog, G. Sybren Liang, Guanzhao Mei, Huan Zheng, Hailin Shen, Yongnian Liu, Weida Med Mycol Case Rep Case Report Chromoblastomycosis is caused by dematiaceous fungi. It develops after inoculation of the organism into the skin. We report a case of chromoblastomycosis in a pulmonary tuberculosis patient without known history of trauma. The lesions were initially diagnosed as sporotrichosis and skin tuberculosis. Histopathology of scales and skin biopsy specimen revealed sclerotic bodies, the hallmark of chromoblastomycosis. The causative organism was identified as Fonsecaea monophora by rDNA ITS sequencing. The lesions recovered markedly after two month treatment with oral terbinafine 250 mg daily according to drug sensitive test in vitro in combination with local thermotherapy Elsevier 2016-05-10 /pmc/articles/PMC4907037/ /pubmed/27330937 http://dx.doi.org/10.1016/j.mmcr.2016.05.001 Text en © 2016 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Shi, Dongmei
Zhang, Wei
Lu, Guixia
de Hoog, G. Sybren
Liang, Guanzhao
Mei, Huan
Zheng, Hailin
Shen, Yongnian
Liu, Weida
Chromoblastomycosis due to Fonsecaea monophora misdiagnosed as sporotrichosis and cutaneous tuberculosis in a pulmonary tuberculosis patient
title Chromoblastomycosis due to Fonsecaea monophora misdiagnosed as sporotrichosis and cutaneous tuberculosis in a pulmonary tuberculosis patient
title_full Chromoblastomycosis due to Fonsecaea monophora misdiagnosed as sporotrichosis and cutaneous tuberculosis in a pulmonary tuberculosis patient
title_fullStr Chromoblastomycosis due to Fonsecaea monophora misdiagnosed as sporotrichosis and cutaneous tuberculosis in a pulmonary tuberculosis patient
title_full_unstemmed Chromoblastomycosis due to Fonsecaea monophora misdiagnosed as sporotrichosis and cutaneous tuberculosis in a pulmonary tuberculosis patient
title_short Chromoblastomycosis due to Fonsecaea monophora misdiagnosed as sporotrichosis and cutaneous tuberculosis in a pulmonary tuberculosis patient
title_sort chromoblastomycosis due to fonsecaea monophora misdiagnosed as sporotrichosis and cutaneous tuberculosis in a pulmonary tuberculosis patient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907037/
https://www.ncbi.nlm.nih.gov/pubmed/27330937
http://dx.doi.org/10.1016/j.mmcr.2016.05.001
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