Investigating polymorphisms by bioinformatics is a potential cost-effective method to screen for germline mutations in Chinese familial adenomatous polyposis patients

The aim of this study was to investigate germline mutations of the APC, MUTYH and AXIN2 genes in Chinese patients with familial adenomatous polyposis (FAP), and further assess the value of bioinformatics in screening the pathogenic changes predisposing to FAP. APC genes from 11 unrelated FAP patient...

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Detalles Bibliográficos
Autores principales: YANG, JUN, LIU, WEI QING, LI, WEN LIANG, CHEN, CHENG, ZHU, ZHU, HONG, MIN, WANG, ZHI QIANG, DONG, JIAN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907044/
https://www.ncbi.nlm.nih.gov/pubmed/27347161
http://dx.doi.org/10.3892/ol.2016.4646

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