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Co-existence of PHF6 and NOTCH1 mutations in adult T-cell acute lymphoblastic leukemia

T-cell acute lymphoblastic leukemia (T-ALL) results from the collaboration of multiple genetic abnormalities in the transformation of T-cell progenitors. Plant homeodomain finger protein 6 (PHF6) has recently been established as a key tumor suppressor, which is mutated in T-ALL; however, the clinica...

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Detalles Bibliográficos
Autores principales: LI, MIN, XIAO, LICHAN, XU, JINGYAN, ZHANG, RUN, GUO, JINGJING, OLSON, JUSTIN, WU, YUJIE, LI, JIANYONG, SONG, CHUNHUA, GE, ZHENG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907067/
https://www.ncbi.nlm.nih.gov/pubmed/27347093
http://dx.doi.org/10.3892/ol.2016.4581