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Co-existence of PHF6 and NOTCH1 mutations in adult T-cell acute lymphoblastic leukemia
T-cell acute lymphoblastic leukemia (T-ALL) results from the collaboration of multiple genetic abnormalities in the transformation of T-cell progenitors. Plant homeodomain finger protein 6 (PHF6) has recently been established as a key tumor suppressor, which is mutated in T-ALL; however, the clinica...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907067/ https://www.ncbi.nlm.nih.gov/pubmed/27347093 http://dx.doi.org/10.3892/ol.2016.4581 |