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Evaluation on antithrombotic effect of aspirin eugenol ester from the view of platelet aggregation, hemorheology, TXB(2)/6-keto-PGF(1α) and blood biochemistry in rat model

BACKGROUND: Based on the prodrug principle, aspirin and eugenol, as starting precursors, were esterified to synthesize aspirin eugenol ester (AEE). The aim of the present study was to evaluate the antithrombotic effect of AEE in an animal disease model. In order to compare the therapeutic effects of...

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Detalles Bibliográficos
Autores principales: Ma, Ning, Liu, Xi-Wang, Yang, Ya-Jun, Shen, Dong-Shuai, Zhao, Xiao-Le, Mohamed, Isam, Kong, Xiao-Jun, Li, Jian-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907079/
https://www.ncbi.nlm.nih.gov/pubmed/27296110
http://dx.doi.org/10.1186/s12917-016-0738-0