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Influence of TP53 and CDH1 genes in hepatocellular cancer spheroid formation and culture: a model system to understand cancer cell growth mechanics

BACKGROUND: Spheroid based culture methods are gaining prominence to elucidate the role of the microenvironment in liver carcinogenesis. Additionally, the phenomenon of epithelial-mesenchymal transition also plays an important role in determining the metastatic potential of liver cancer. Tumor spher...

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Detalles Bibliográficos
Autores principales:	Pomo, Joseph M., Taylor, Robert M., Gullapalli, Rama R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907104/ https://www.ncbi.nlm.nih.gov/pubmed/27303212 http://dx.doi.org/10.1186/s12935-016-0318-1

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