Mucosal and blood-brain barrier transport kinetics of the plant N-alkylamide spilanthol using in vitro and in vivo models

BACKGROUND: N-alkylamides (NAAs) are a large group of secondary metabolites occurring in more than 25 plant families which are often used in traditional medicine. A prominent active NAA is spilanthol. The general goal was to quantitatively investigate the gut mucosa and blood-brain barrier (BBB) per...

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Detalles Bibliográficos
Autores principales: Veryser, Lieselotte, Taevernier, Lien, Joshi, Tanmayee, Tatke, Pratima, Wynendaele, Evelien, Bracke, Nathalie, Stalmans, Sofie, Peremans, Kathelijne, Burvenich, Christian, Risseeuw, Martijn, De Spiegeleer, Bart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907212/
https://www.ncbi.nlm.nih.gov/pubmed/27296455
http://dx.doi.org/10.1186/s12906-016-1159-0

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