Cargando…

HIV-1 Protease, Reverse Transcriptase, and Integrase Variation

HIV-1 protease (PR), reverse transcriptase (RT), and integrase (IN) variability presents a challenge to laboratories performing genotypic resistance testing. This challenge will grow with increased sequencing of samples enriched for proviral DNA such as dried blood spots and increased use of next-ge...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rhee, Soo-Yon, Sankaran, Kris, Varghese, Vici, Winters, Mark A., Hurt, Christopher B., Eron, Joseph J., Parkin, Neil, Holmes, Susan P., Holodniy, Mark, Shafer, Robert W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2016
Materias:	Genetic Diversity and Evolution
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907232/ https://www.ncbi.nlm.nih.gov/pubmed/27099321 http://dx.doi.org/10.1128/JVI.00495-16

Ejemplares similares

Development of Elvitegravir Resistance and Linkage of Integrase Inhibitor Mutations with Protease and Reverse Transcriptase Resistance Mutations
por: Winters, Mark A., et al.
Publicado: (2012)

Fitness Barriers Limit Reversion of a Proofreading-Deficient Coronavirus
por: Graepel, Kevin W., et al.
Publicado: (2019)

Rapid SARS-CoV-2 Adaptation to Available Cellular Proteases
por: Chaudhry, M. Zeeshan, et al.
Publicado: (2022)

Predicting Permissive Mutations That Improve the Fitness of A(H1N1)pdm09 Viruses Bearing the H275Y Neuraminidase Substitution
por: Farrukee, Rubaiyea, et al.
Publicado: (2022)

Dengue virus serotypic replacement of NS3 protease or helicase domain causes chimeric viral attenuation but can be recovered by a compensated mutation at helicase domain or NS2B, respectively
por: Teramoto, Tadahisa
Publicado: (2023)

Antarctic Penguins as Reservoirs of Diversity for Avian Avulaviruses
por: Wille, Michelle, et al.
Publicado: (2019)

Evidence for the Introduction, Reassortment, and Persistence of Diverse Influenza A Viruses in Antarctica
por: Hurt, Aeron C., et al.
Publicado: (2016)

Comparative Analysis of RNA Virome Composition in Rabbits and Associated Ectoparasites
por: Mahar, Jackie E., et al.
Publicado: (2020)

Metatranscriptomic Analysis of Virus Diversity in Urban Wild Birds with Paretic Disease
por: Chang, Wei-Shan, et al.
Publicado: (2020)

A Diverse Range of Novel RNA Viruses in Geographically Distinct Honey Bee Populations
por: Remnant, Emily J., et al.
Publicado: (2017)

Divergent Evolutionary Pathways of Myxoma Virus in Australia: Virulence Phenotypes in Susceptible and Partially Resistant Rabbits Indicate Possible Selection for Transmissibility
por: Kerr, Peter J., et al.
Publicado: (2022)

Fecal Viral Diversity of Captive and Wild Tasmanian Devils Characterized Using Virion-Enriched Metagenomics and Metatranscriptomics
por: Chong, Rowena, et al.
Publicado: (2019)

Diverse RNA Viruses Associated with Diatom, Eustigmatophyte, Dinoflagellate, and Rhodophyte Microalgae Cultures
por: Charon, Justine, et al.
Publicado: (2022)

Extensive Diversity of RNA Viruses in Australian Ticks
por: Harvey, Erin, et al.
Publicado: (2019)

Complete genome reconstruction of the global and European regional dispersal history of the lumpy skin disease virus
por: Van Borm, Steven, et al.
Publicado: (2023)

Genome Number and Size Polymorphism in Zika Virus Infectious Units
por: Sexton, Nicole R., et al.
Publicado: (2021)

Punctuated Loci on Chromosome IV Determine Natural Variation in Orsay Virus Susceptibility of Caenorhabditis elegans Strains Bristol N2 and Hawaiian CB4856
por: Sterken, Mark G., et al.
Publicado: (2021)

Single-Genome Sequencing of Hepatitis C Virus in Donor-Recipient Pairs Distinguishes Modes and Models of Virus Transmission and Early Diversification
por: Li, Hui, et al.
Publicado: (2015)

Weaker HLA Footprints on HIV in the Unique and Highly Genetically Admixed Host Population of Mexico
por: Soto-Nava, Maribel, et al.
Publicado: (2018)

Phylodynamics of Enterovirus A71-Associated Hand, Foot, and Mouth Disease in Viet Nam
por: Geoghegan, Jemma L., et al.
Publicado: (2015)

HIV-1 Subtype B Protease and Reverse Transcriptase Amino Acid Covariation
por: Rhee, Soo-Yon, et al.
Publicado: (2007)

Unfixed Endogenous Retroviral Insertions in the Human Population
por: Marchi, Emanuele, et al.
Publicado: (2014)

Deep Sequencing of Norovirus Genomes Defines Evolutionary Patterns in an Urban Tropical Setting
por: Cotten, Matthew, et al.
Publicado: (2014)

Powerful Sequence Similarity Search Methods and In-Depth Manual Analyses Can Identify Remote Homologs in Many Apparently “Orphan” Viral Proteins
por: Kuchibhatla, Durga B., et al.
Publicado: (2014)

Stability of the Parainfluenza Virus 5 Genome Revealed by Deep Sequencing of Strains Isolated from Different Hosts and following Passage in Cell Culture
por: Rima, Bert K., et al.
Publicado: (2014)

Genome Diversity of Epstein-Barr Virus from Multiple Tumor Types and Normal Infection
por: Palser, Anne L., et al.
Publicado: (2015)

Local Evolutionary Patterns of Human Respiratory Syncytial Virus Derived from Whole-Genome Sequencing
por: Agoti, Charles N., et al.
Publicado: (2015)

Sinorhizobium meliloti Phage ΦM9 Defines a New Group of T4 Superfamily Phages with Unusual Genomic Features but a Common T=16 Capsid
por: Johnson, Matthew C., et al.
Publicado: (2015)

Novel Denisovan and Neanderthal Retroviruses
por: Lee, Adam, et al.
Publicado: (2014)

Accumulation of Human-Adapting Mutations during Circulation of A(H1N1)pdm09 Influenza Virus in Humans in the United Kingdom
por: Elderfield, Ruth A., et al.
Publicado: (2014)

Evolution of Cocirculating Varicella-Zoster Virus Genotypes during a Chickenpox Outbreak in Guinea-Bissau
por: Depledge, Daniel P., et al.
Publicado: (2014)

Molecular Evolutionary Dynamics of Respiratory Syncytial Virus Group A in Recurrent Epidemics in Coastal Kenya
por: Otieno, James R., et al.
Publicado: (2016)

Increasing Clinical Severity during a Dengue Virus Type 3 Cuban Epidemic: Deep Sequencing of Evolving Viral Populations
por: Rodriguez-Roche, Rosmari, et al.
Publicado: (2016)

Genetic Stability of Bacterial Artificial Chromosome-Derived Human Cytomegalovirus during Culture In Vitro
por: Murrell, Isa, et al.
Publicado: (2016)

Salmon Gill Poxvirus, the Deepest Representative of the Chordopoxvirinae
por: Gjessing, Mona C., et al.
Publicado: (2015)

Molecular Epidemiology and Evolution of Influenza Viruses Circulating within European Swine between 2009 and 2013
por: Watson, Simon J., et al.
Publicado: (2015)

Genetics, Receptor Binding, Replication, and Mammalian Transmission of H4 Avian Influenza Viruses Isolated from Live Poultry Markets in China
por: Liang, Libin, et al.
Publicado: (2016)

Spatial-Temporal Patterns of Viral Amplification and Interference Initiated by a Single Infected Cell
por: Akpinar, Fulya, et al.
Publicado: (2016)

Characterizing the Diverse Mutational Pathways Associated with R5-Tropic Maraviroc Resistance: HIV-1 That Uses the Drug-Bound CCR5 Coreceptor
por: Jiang, Xiaowei, et al.
Publicado: (2015)

Successive Respiratory Syncytial Virus Epidemics in Local Populations Arise from Multiple Variant Introductions, Providing Insights into Virus Persistence
por: Agoti, Charles N., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_o1bdill0bs17an1o5rl8g1ds27