Improved data analysis for the MinION nanopore sequencer

The Oxford Nanopore MinION sequences individual DNA molecules using an array of pores that read nucleotide identities based on ionic current steps. We evaluated and optimized MinION performance using M13 genomic dsDNA. Using expectation-maximization (EM) we obtained robust maximum likelihood (ML) es...

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Detalles Bibliográficos
Autores principales: Jain, Miten, Fiddes, Ian, Miga, Karen H., Olsen, Hugh E., Paten, Benedict, Akeson, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907500/
https://www.ncbi.nlm.nih.gov/pubmed/25686389
http://dx.doi.org/10.1038/nmeth.3290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907500/
https://www.ncbi.nlm.nih.gov/pubmed/25686389
http://dx.doi.org/10.1038/nmeth.3290

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