Role of Human Breast Cancer Related Protein versus P-Glycoprotein as an Efflux Transporter for Benzylpenicillin: Potential Importance at the Blood-Brain Barrier

While the blood-brain barrier (BBB) protects the brain by controlling the access of solutes and toxic substances to brain, it also limits drug entry to treat central nervous system disorders. Many drugs are substrates for ATP-binding cassette (ABC) transporters at the BBB that limit their entry into...

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Detalles Bibliográficos
Autores principales: Li, Yangfang, Wu, Qian, Li, Chen, Liu, Ling, Du, Kun, Shen, Jin, Wu, Yuqin, Zhao, Xiaofen, Zhao, Mei, Bao, Lingyun, Gao, Jin, Keep, Richard F., Xiang, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907523/
https://www.ncbi.nlm.nih.gov/pubmed/27300692
http://dx.doi.org/10.1371/journal.pone.0157576

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