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Intratracheal instillation of ethyl pyruvate nanoparticles prevents the development of shunt-flow-induced pulmonary arterial hypertension in a rat model

PURPOSE: To investigate whether inhalation of ethyl pyruvate (EP) encapsulated with poly(ethylene glycol)-block-lactide/glycolide copolymer nanoparticles (EP-NPs) can prevent the development of shunt-flow-induced hyperkinetic pulmonary arterial hypertension (PAH) in a rat model. MATERIALS AND METHOD...

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Detalles Bibliográficos
Autores principales:	Liu, Kai, Zhang, Xiquan, Cao, Guangqing, Liu, Yongjun, Liu, Chuanzhen, Sun, Hourong, Pang, Xinyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907741/ https://www.ncbi.nlm.nih.gov/pubmed/27354791 http://dx.doi.org/10.2147/IJN.S103183

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