Next-generation sequencing in neuropathologic diagnosis of infections of the nervous system

OBJECTIVE: To determine the feasibility of next-generation sequencing (NGS) microbiome approaches in the diagnosis of infectious disorders in brain or spinal cord biopsies in patients with suspected CNS infections. METHODS: In a prospective pilot study, we applied NGS in combination with a new compu...

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Detalles Bibliográficos
Autores principales: Salzberg, Steven L., Breitwieser, Florian P., Kumar, Anupama, Hao, Haiping, Burger, Peter, Rodriguez, Fausto J., Lim, Michael, Quiñones-Hinojosa, Alfredo, Gallia, Gary L., Tornheim, Jeffrey A., Melia, Michael T., Sears, Cynthia L., Pardo, Carlos A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907805/
https://www.ncbi.nlm.nih.gov/pubmed/27340685
http://dx.doi.org/10.1212/NXI.0000000000000251

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