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Drug nanocrystals: A way toward scale-up
Drug nanocrystals comprise unique drug delivery platforms playing a significantly important and distinctive role in drug delivery and as such, the industry and academia are spending a lot of their time and money in developing the nanocrystal products. The current research works in this field depict...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908054/ https://www.ncbi.nlm.nih.gov/pubmed/27330370 http://dx.doi.org/10.1016/j.jsps.2014.04.007 |
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author | Raghava Srivalli, Kale Mohana Mishra, Brahmeshwar |
author_facet | Raghava Srivalli, Kale Mohana Mishra, Brahmeshwar |
author_sort | Raghava Srivalli, Kale Mohana |
collection | PubMed |
description | Drug nanocrystals comprise unique drug delivery platforms playing a significantly important and distinctive role in drug delivery and as such, the industry and academia are spending a lot of their time and money in developing the nanocrystal products. The current research works in this field depict a vivid shift from lab scale optimization studies to scale up focused studies. In this emerging scenario of nanocrystal technology, a review on some exemplary and progressing research studies with either scalability as their objective or upscaling as their future scope may smoothen the future upscaling attempts in this field. Hence, this paper reviews the efforts of such research works as case studies since an analysis of such research studies may input certain beneficial knowledge to carry out more scale up based research works on nanocrystals. |
format | Online Article Text |
id | pubmed-4908054 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-49080542016-06-21 Drug nanocrystals: A way toward scale-up Raghava Srivalli, Kale Mohana Mishra, Brahmeshwar Saudi Pharm J Review Drug nanocrystals comprise unique drug delivery platforms playing a significantly important and distinctive role in drug delivery and as such, the industry and academia are spending a lot of their time and money in developing the nanocrystal products. The current research works in this field depict a vivid shift from lab scale optimization studies to scale up focused studies. In this emerging scenario of nanocrystal technology, a review on some exemplary and progressing research studies with either scalability as their objective or upscaling as their future scope may smoothen the future upscaling attempts in this field. Hence, this paper reviews the efforts of such research works as case studies since an analysis of such research studies may input certain beneficial knowledge to carry out more scale up based research works on nanocrystals. Elsevier 2016-07 2014-05-09 /pmc/articles/PMC4908054/ /pubmed/27330370 http://dx.doi.org/10.1016/j.jsps.2014.04.007 Text en © 2014 King Saud University. Production and hosting by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/). |
spellingShingle | Review Raghava Srivalli, Kale Mohana Mishra, Brahmeshwar Drug nanocrystals: A way toward scale-up |
title | Drug nanocrystals: A way toward scale-up |
title_full | Drug nanocrystals: A way toward scale-up |
title_fullStr | Drug nanocrystals: A way toward scale-up |
title_full_unstemmed | Drug nanocrystals: A way toward scale-up |
title_short | Drug nanocrystals: A way toward scale-up |
title_sort | drug nanocrystals: a way toward scale-up |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908054/ https://www.ncbi.nlm.nih.gov/pubmed/27330370 http://dx.doi.org/10.1016/j.jsps.2014.04.007 |
work_keys_str_mv | AT raghavasrivallikalemohana drugnanocrystalsawaytowardscaleup AT mishrabrahmeshwar drugnanocrystalsawaytowardscaleup |