Morphologic Damage of Rat Alveolar Epithelial Type II Cells Induced by Bile Acids Could Be Ameliorated by Farnesoid X Receptor Inhibitor Z-Guggulsterone In Vitro

Objective. To determine whether bile acids (BAs) affect respiratory functions through the farnesoid X receptor (FXR) expressed in the lungs and to explore the possible mechanisms of BAs-induced respiratory disorder. Methods. Primary cultured alveolar epithelial type II cells (AECIIs) of rat were tre...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Jieqin, Huang, Yaowei, Hou, Xusheng, Wu, Wenyu, Nie, Lei, Tian, Yinghong, Lu, Yanmeng, Yin, Yanru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908247/
https://www.ncbi.nlm.nih.gov/pubmed/27340672
http://dx.doi.org/10.1155/2016/9283204

Ejemplares similares

Ejemplares similares