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Animal Models of Cystic Fibrosis Pathology: Phenotypic Parallels and Divergences

Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The resultant characteristic ion transport defect results in decreased mucociliary clearance, bacterial colonisation, and chronic neutrophil-dominated inflammation. Much knowledge surr...

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Detalles Bibliográficos
Autores principales:	Lavelle, Gillian M., White, Michelle M., Browne, Niall, McElvaney, Noel G., Reeves, Emer P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908263/ https://www.ncbi.nlm.nih.gov/pubmed/27340661 http://dx.doi.org/10.1155/2016/5258727

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