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Data-driven mechanistic analysis method to reveal dynamically evolving regulatory networks
Motivation: Mechanistic models based on ordinary differential equations provide powerful and accurate means to describe the dynamics of molecular machinery which orchestrates gene regulation. When combined with appropriate statistical techniques, mechanistic models can be calibrated using experiment...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908358/ https://www.ncbi.nlm.nih.gov/pubmed/27307629 http://dx.doi.org/10.1093/bioinformatics/btw274 |