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A novel algorithm for calling mRNA m(6)A peaks by modeling biological variances in MeRIP-seq data
Motivation: N(6)-methyl-adenosine (m(6)A) is the most prevalent mRNA methylation but precise prediction of its mRNA location is important for understanding its function. A recent sequencing technology, known as Methylated RNA Immunoprecipitation Sequencing technology (MeRIP-seq), has been developed...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908365/ https://www.ncbi.nlm.nih.gov/pubmed/27307641 http://dx.doi.org/10.1093/bioinformatics/btw281 |