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Modulation of the Mesenchymal Stem Cell Secretome Using Computer-Controlled Bioreactors: Impact on Neuronal Cell Proliferation, Survival and Differentiation
In recent years it has been shown that the therapeutic benefits of human mesenchymal stem/stromal cells (hMSCs) in the Central Nervous System (CNS) are mainly attributed to their secretome. The implementation of computer-controlled suspension bioreactors has shown to be a viable route for the expans...
Autores principales: | Teixeira, Fábio G., Panchalingam, Krishna M., Assunção-Silva, Rita, Serra, Sofia C., Mendes-Pinheiro, Bárbara, Patrício, Patrícia, Jung, Sunghoon, Anjo, Sandra I., Manadas, Bruno, Pinto, Luísa, Sousa, Nuno, Behie, Leo A., Salgado, António J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908397/ https://www.ncbi.nlm.nih.gov/pubmed/27301770 http://dx.doi.org/10.1038/srep27791 |
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