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Longitudinal monitoring of immunoglobulin A glycosylation during pregnancy by simultaneous MALDI-FTICR-MS analysis of N- and O-glycopeptides

Immunoglobulin A (IgA) is a glycoprotein of which altered glycosylation has been associated with several pathologies. Conventional methods for IgA N- and O-glycosylation analysis are tedious, thus limiting such analyses to small sample sizes. Here we present a high-throughput strategy for the simult...

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Detalles Bibliográficos
Autores principales:	Bondt, Albert, Nicolardi, Simone, Jansen, Bas C., Stavenhagen, Kathrin, Blank, Dennis, Kammeijer, Guinevere S. M., Kozak, Radoslaw P., Fernandes, Daryl L., Hensbergen, Paul J., Hazes, Johanna M. W., van der Burgt, Yuri E. M., Dolhain, Radboud J. E. M., Wuhrer, Manfred
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908400/ https://www.ncbi.nlm.nih.gov/pubmed/27302155 http://dx.doi.org/10.1038/srep27955

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