Angiotensin-converting enzyme 2 prevents lipopolysaccharide-induced rat acute lung injury via suppressing the ERK1/2 and NF-κB signaling pathways

Acute respiratory distress syndrome (ARDS) caused by severe sepsis remains a major challenge in intensive care medicine. ACE2 has been shown to protect against lung injury. However, the mechanisms of its protective effects on ARDS are largely unknown. Here, we report that ACE2 prevents LPS-induced A...

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Detalles Bibliográficos
Autores principales: Li, Yingchuan, Zeng, Zhen, Cao, Yongmei, Liu, Yujing, Ping, Feng, Liang, Mengfan, Xue, Ying, Xi, Caihua, Zhou, Ming, Jiang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908402/
https://www.ncbi.nlm.nih.gov/pubmed/27302421
http://dx.doi.org/10.1038/srep27911

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