INPP4B is an oncogenic regulator in human colon cancer

Inositol polyphosphate 4-phosphatase type II (INPP4B) negatively regulates phosphatidylinositol 3-kinase signaling and is a tumor suppressor in some types of cancers. However, we have found that it is frequently upregulated in human colon cancer cells. Here we show that silencing of INPP4B blocks ac...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, S T, Chi, M N, Yang, R H, Guo, X Y, Zan, L K, Wang, C Y, Xi, Y F, Jin, L, Croft, A, Tseng, H-Y, Yan, X G, Farrelly, M, Wang, F H, Lai, F, Wang, J F, Li, Y P, Ackland, S, Scott, R, Agoulnik, I U, Hondermarck, H, Thorne, R F, Liu, T, Zhang, X D, Jiang, C C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908438/
https://www.ncbi.nlm.nih.gov/pubmed/26411369
http://dx.doi.org/10.1038/onc.2015.361

Ejemplares similares

Ejemplares similares