Gain of function AMP‐activated protein kinase γ3 mutation (AMPK γ3(R200Q)) in pig muscle increases glycogen storage regardless of AMPK activation

Chronic activation of AMP‐activated protein kinase (AMPK) increases glycogen content in skeletal muscle. Previously, we demonstrated that a mutation in the ryanodine receptor (RyR1(R615C)) blunts AMPK phosphorylation in longissimus muscle of pigs with a gain of function mutation in the AMPK γ3 subun...

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Detalles Bibliográficos
Autores principales: Scheffler, Tracy L., Park, Sungkwon, Roach, Peter J., Gerrard, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908487/
https://www.ncbi.nlm.nih.gov/pubmed/27302990
http://dx.doi.org/10.14814/phy2.12802

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