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Limiting collagen turnover via collagenase‐resistance attenuates right ventricular dysfunction and fibrosis in pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH) is a severe form of pulmonary hypertension in which right ventricular (RV) afterload is increased and death typically occurs due to decompensated RV hypertrophy and failure. Collagen accumulation has been implicated in pulmonary artery remodeling, but how it aff...

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Detalles Bibliográficos
Autores principales:	Golob, Mark J., Wang, Zhijie, Prostrollo, Anthony J., Hacker, Timothy A., Chesler, Naomi C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908492/ https://www.ncbi.nlm.nih.gov/pubmed/27252252 http://dx.doi.org/10.14814/phy2.12815

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