Cargando…

Crystal structure of (1S,3R,8R,10S)-2,2-di­chloro-10-hy­droxy-3,7,7,10-tetra­methyl­tri­cyclo­[6.4.0.0(1,3)]dodecan-9-one

The asymmetric unit of the title compound, C(16)H(24)Cl(2)O(2), contains two independent mol­ecules (A and B) which are built from three fused rings, viz. a seven-membered heptane ring, a six-membered cyclo­hexyl ring bearing a ketone and an alcohol group, and a cyclo­propane ring bearing two Cl ato...

Descripción completa

Detalles Bibliográficos
Autores principales: Benzalim, Ahmed, Auhmani, Aziz, Ait Itto, My Youssef, Daran, Jean-Claude, Abdelwahed, Auhmani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908527/
https://www.ncbi.nlm.nih.gov/pubmed/27308024
http://dx.doi.org/10.1107/S2056989016006174
Descripción
Sumario:The asymmetric unit of the title compound, C(16)H(24)Cl(2)O(2), contains two independent mol­ecules (A and B) which are built from three fused rings, viz. a seven-membered heptane ring, a six-membered cyclo­hexyl ring bearing a ketone and an alcohol group, and a cyclo­propane ring bearing two Cl atoms. In the crystal, the two mol­ecules are linked via two O—H⋯O hydrogen bonds, forming an A–B dimer with an R (2) (2)(10) ring motif. The A mol­ecules of these dimers are linked via a C—H⋯O hydrogen bond, forming chains propagating along the a-axis direction. Both mol­ecules have the same absolute configuration, i.e. 1S,3R,8R,10S, which is based on the synthetic pathway and further confirmed by resonant scattering [Flack parameter = 0.03 (5)].