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Fusing simulation and experiment: The effect of mutations on the structure and activity of the influenza fusion peptide
During the infection process, the influenza fusion peptide (FP) inserts into the host membrane, playing a crucial role in the fusion process between the viral and host membranes. In this work we used a combination of simulation and experimental techniques to analyse the molecular details of this pro...
Autores principales: | Lousa, Diana, Pinto, Antónia R. T., Victor, Bruno L., Laio, Alessandro, Veiga, Ana S., Castanho, Miguel A. R. B., Soares, Cláudio M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908596/ https://www.ncbi.nlm.nih.gov/pubmed/27302370 http://dx.doi.org/10.1038/srep28099 |
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